Versatile transcription control based on reversible dCas9 binding
نویسندگان
چکیده
منابع مشابه
dCas9: A Versatile Tool for Epigenome Editing.
The epigenome is a heritable layer of information not encoded in the DNA sequence of the genome, but in chemical modifications of DNA or histones. These chemical modifications, together with transcription factors, operate as spatiotemporal regulators of genome activity. Dissecting epigenome function requires controlled site-specific alteration of epigenetic information. Such control can be obta...
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ژورنال
عنوان ژورنال: RNA
سال: 2019
ISSN: 1355-8382,1469-9001
DOI: 10.1261/rna.071613.119